Sulforaphane adhd reddit. Sulforaphane reverses all these effects.

Sulforaphane adhd reddit A couple of links below. Nearly a million and a half users say they 'feel at home' and 'finally found a place where people understand them'. Broq (sulforaphane) - How to mitigate temporary, negative physical effects I’ve been trying to give Broq a shot, but I’m having real issues for roughly an hour after taking it (whether it’s the half or full dose). Also, hormesis isn’t just the notion that “bad” things are good for us. Sulforaphane for improvement in SCT/ADHD symptoms So, I’ve been taking Sulforaphane for the last 2 months and it has improved my ability to have mental clarity, focus and calmness. Sulforaphane = broccoli sprouts Epicatechin = cocoa powder Will supplementing with these generally have any noticeable effect on muscle development as apposed to not having them in your diet? For the uninitiated, Myostatin is a hormones' that tells muscles not to get too big. Business, Economics, and Finance. SCT was short for Sluggish Cognitive Tempo. Sulforaphane is not a magic cure and I still talk too fast, say offensive things without meaning to once in a while, and overall struggle to socialize with people. I'm more calm, collected, less annoyed by stimuli, and sleep better. Proceedings of the National Academy of Sciences, 111(43), 15550-15555. If given enough time—such as when sitting in your upper stomach waiting to get digested—sulforaphane is born. Ok, fair enough. Sulforaphane from broccoli reduces symptoms of autism: a follow-up case series from a randomized double-blind study. 1-0. Not a place for discussion of illicit and illegal compounds. there are supplements out there that can increase your body’s natural glutathione pools on top of other Hi, I’m new to this Reddit but am taking this supplement in support of liver detox for oestrogen dominance. I did some research earlier and found a thread where someone explained why it's bad to take both NAC and sulforaphane together because the NAC does something which undermines the hermetic mechanism of sulforaphane, although it was a little over my head. They all act as releasing agents for catecholamines (i. In short, young red radish sprouts harvested at their nutritional peak were kept at No heard about it but isn't good idea to try substances that never weren't tested in large scale clinical trials ,suplements especially from plants can often be dangerous and have serious side effects after some time of usage. It is a distinct disorder which is frequently misdiagnosed as ADHD-PI, although it is possible to have both, and they are often comorbid. Singh K, et al. Was curious if there are any unwanted interactions I should be aware of. Members Online Fynria Just a heads up on this. amazon has added quite few new sulforaphane products, and some of them can be quite expensive. I keep hearing about the extraordinary benefits of sulforaphane, but it appears that very few "sulforaphane" supplements actually contain any sulforaphane at all. nlm. All the others depend on conversion from glucoraphanin. The dosage recommended in what I’ve read is 100mg every other day- I’m struggling to get past 35 as this supplement is gassy AF and I have IBS. This thread is archived New comments cannot be posted and votes cannot be cast you’re right in a sense but he has a low grade autism spectrum disorder meaning he can function but obviously has the retrospects and symptoms of autism but quelled enough for him to be able to go to school and soon enough, go to college. We're an inclusive, disability-oriented peer support group for people with ADHD with an emphasis on science-backed information. Do some basic math and you would have to eat over 40 pounds of fruits and veggies at once to reach toxic levels, you would likely reach oxalate toxicity and toxicity from other compounds much much sooner. Just wondering if anyone has anymore information regarding this, or maybe I read the study wrong? Sulforaphane isn't simply there from the beginning, it's produced in the body through reaction with the myrosinase enzyme. We also do speech and OT. While digging around for anecdotes on sulforaphane use, i stumbled upon a post in a keto subreddit. Share your stories, struggles, and non-medication strategies. However, I also take BROQ sulforaphane daily. They claim this contains both glucoraphanin and active myrosinase. I suddenly felt like my ADHD meds were 2x the amount and last twice as long. I did not look in too much information on the cancer fighting properties, so if I have a false interpretation of the effects of sulforaphane pls correct me! Sep 18, 2023 · Sulforaphane has been shown to improve social interaction and communication skills in individuals with autism, and it may be able to reduce oxidative stress and inflammation in the brain. 4 milligrams, mg) per capsule. Rhonda Patrick recommendations and takes. Note: this is a community for in-depth discussions, not a dumping ground for memes The temp disables the enzyme that creates sulforaphane nitriles vs sulforaphane from the precursor. 7-9. The broccoli sprouts have other benefits for autism and ADHD besides sulforaphane that are still present in mature broccoli, so I definitely recommending eating lots of broccoli. Omega 3 NAC (cycled) DIM & sulforaphane (150 MG taken at meals) Calcium d… Without touching on whether he sulforaphane actually works, the only argument in that link is that the author thinks the fact that its metabolites are detected in urine within 3 hours means the body doesn’t want it and it therefore must be bad. This is an estimated human dose of: 1. 00 μM after 1 hour and declining with first-order kinetics, with a mean half-life of 1. University of Illinois Urbana Champaign has been doing ongoing research on the most effective ways of cooking broccoli and pairing with other ingredients such as horseradish, mustard, and wasabi to maximize the levels and even restore from commercially frozen broccoli. As a consequence, we propose that the excreted amount of sulforaphane metabolites (sulforaphane + sulforaphane cysteine-glycine + sulforaphane cysteine + sulforaphane N-acetylcysteine) in urine over 24 h (2–3 half-lives), which is a measure of “internal dose”, provides a more revealing and likely consistent view of the delivery of Super expensive supplement, can’t figure out how to tolerate it, no time to consume when optima or unwilling to take it in the am, dismissive of the natural (and still efficacious) source… it seems like your thoughts on the matter are inflexible to the point of you not having many options for long term sustainability. A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. No medical questions. 5 mg for a 150lb person 1. It also might have been a reason why my general memory has also improved but that could be to the adderall and nootropics I take in combination with Sulforaphane. Lynch R, et al. 2 mg for a 200lb person 1. 29) lipophilic organosulfur compound or isothiocyanate (1-isothiocyanato-4-(methylsulfinyl)butane) currently under Short answer: no. gov/15184012/ Ye et al. But it did help me quite a lot. If you have the focus for books - Brain Hacks by Lara Honos-Webb, PhD is a great breakdown of ADHD as an executive function disorder and tips and coping methods to try out. It is produced when the enzyme myrosinase transforms glucoraphanin, a glucosinolate, into sulforaphane upon damage to the plant (such as from chewing), which allows the two compounds to mix and react. 158K subscribers in the DrugNerds community. We haven’t tried everything so far, but I’ll outline what we have done: Sulforaphane is an Nrf2-activation based phytochemical. Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by symptoms such as inattention, hyperactivity, and impulsivity. Be careful with it when taking other medications Made me very agitated for the day https://pubmed. Yep. A sulforaphane-rich broccoli sprout/red radish sprout powder mix was prepared using BroccoPhane ®, a broccoli sprout powder standardized for sulforaphane (Bioriginal, Den Bommel, The Netherlands, Europe), and radish sprout powder produced in local laboratories. Prostaphane is the only supplement that’s worth it, every other once doesn’t even match the sulforaphane content of 100g of broccoli sprouts (40mg of sulforaphane). Methods We conducted a 15-week randomized Action Movies & Series; Animated Movies & Series; Comedy Movies & Series; Crime, Mystery, & Thriller Movies & Series; Documentary Movies & Series; Drama Movies & Series 77 votes, 117 comments. For the discussion of recreational pharmacology. As I under, the highest bioavailability is Sulforaphane, but Sulforaphane is not stable and supplements may not be potent and have degraded. good luck Apr 29, 2020 · Sulforaphane (1-isothiocyanato-4-methylsulfinylbutane; ACER, Tehran, Iran) was prescribed at 50 μmol and 100 μmol (approximately 10 mg and 20 mg) per day for patients weighing <45 kg and 45–90 kg, respectively. SFN is a small molecular weight (molecular weight = 177. I'm guessing this is because the compound is actually very unstable, so it would just break down and conpletely lose potency if put into capsules. It is an effective activator of the transcription factor nuclear erythroid-2 like factor-2, which can upregulate multiple antioxidants and protect neurons against various oxidative damages. If you are more into podcasts, ADHD-rewired is great! Lots of interviews and adhd coaching. showed that after a single 200 μmol oral dose of sulforaphane both sulforaphane and its metabolites were detected in plasma and erythrocytes in just 15 minutes, peaking in all four subjects at ~2. r/AutisticWithADHD: Community for autistic people with ADHD to ask advice, vent about your day, share stories, infodump on your special interests and… No heard about it but isn't good idea to try substances that never weren't tested in large scale clinical trials ,suplements especially from plants can often be dangerous and have serious side effects after some time of usage. im more interested in the benefits for brain function. ive tried 2 different brands, with no results. Summary: Sulforaphane (SFN) in a plant derived compound (phytochemical) present in cruciferous vegetables, most notably broccoli (Brassica oleracea) and broccoli sprouts. Even the plants keep it conjugated as glucoraphanin, which must be enzymatically cleaved by myrosinase to form an intermediate product, which then must avoid reacting with epithiospecifier protein (ESP) to become sulforaphane. sulforaphane can help with adhd and autistic symptoms. [42] There is no “cure” for autism, and that is never what I would seek. I have just seen this as part of a study about Sulforaphane Conclusions Hyperammonemia-induced neuroinflammation impairs glutamatergic and GABAergic neurotransmission by altering membrane expression of glutamate and GABA receptors, resulting in impaired spatial learning. Other members include cabbage (green, red, savoy, napa, etc), collards, arugula, brocoli, cauliflower and many others. On the other are stabilized version (?) of Sulforaphane. For people with adhd they might not be releasing their dopamine in a way that is productive (such as restless leg syndrome / wandering thoughts / activity that doesn't match the situation at hand [so hyperactivity or fatigue]) inhibiting the release could lead to increased focus as the brain isn't "wasting" the dopamine it needs on "useless Posted by u/Acceptable_Berry_393 - 5 votes and 11 comments Community for autistic people with ADHD to ask advice, vent about your day, share stories, infodump on your special interests and most importantly: be yourself. Here are some of the most commonly taken sulforaphane supplement brands in the United States: BrocElite Swanson Sulforaphane Best Naturals Broccoli Sprouts Extract Jarrow Formulas BroccoMax Thorne Crucera-SGS Life Extension Sulforaphane Glucosinolate BROQ is what Dr. Moreover, it doesn't make much sense to talk about 'high tonic' release in isolation, as the autoreceptor activating doses of stimulants not only decrease tonic but also phasic release, so it is the ratio of tonic to phasic that matters, which is a two-dimensional function. Couldn’t find anything directly when I did a quick google search, but have read that Sulforaphane may inhibit the breaking down of some molecules. Everybody knows that sulforaphane is a pesticide and toxic to humans at high enough levels. Risperidone and sulforaphane/placebo treatments were initiated simultaneously. Here's my current stack for slow comt, anxiety, and estrogen dominance. I recommend checking it out for more info. A major part of the claimed benefits are in my opinion because of the increased glutathione production. Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. but im not sure all of them are good quality. I can definetly recommend this if you struggle with adhd! And yeah, finding what works to help manage ADHD is a constant process lol. This is because how amphetamines and related structural analogs (such as phenylethylamines, phenylmorpholines, etc. When I took it today it felt legitimately like a low dose of dextroamphetamine without the heart racing/nervousness effects, in fact it seemed to help my ADHD more effectively than dexedrine, my mind was calm but very focused and it felt more like what ADHD meds "should" feel like. Members Online Front_Equivalent_635 I recently purchased a sulforaphane supplement thinking it would help my testosterone and health overall, but then I came across a study about mice that were given it for hair regrowth, and that it lowered their blood testosterone levels. most research is about cancer which i dont care about as much, althought my grandma died from it and my grandpa has prostate cancer currently so its in my family. From the wiki page I linked: Its mechanism of action in the treatment of ADHD is to increase noradrenergic tone in the prefrontal cortex (PFC) directly by binding to postsynaptic α2A adrenergic receptors and indirectly by increasing norepinephrine input from the locus coeruleus. ) work. so can high dose omega 3s - mix of dha and epa, 2-5 gram range, make sure you get one with a low totox value. The studies on the consumption of sulforaphane and its associative decrease in all cause mortality are quite robust. 5mg/kg sulforaphane to rats has been noted to be bioactive. Posted by u/Zypher1796 - 1 vote and no comments Not Sulforaphane glucosinolate from broccoli seeds extract which only has a very small percentage of Sulforaphane. 77 ± 0. Sulforaphane reverses all these effects. GameStop Moderna Pfizer Johnson & Johnson AstraZeneca Walgreens Best Buy Novavax SpaceX Tesla. Sulforaphane is an unstable compound. Sulforaphane treatment of autism spectrum disorder (ASD). Sulforaphane, being rich in cruciferous vegetables, mostly broccoli and cabbage, and brussel sprouts. I have adhd and have tried a lot of nootropics to help me with it and for 3 months now I take neurostim extracts from mindnutrition and it has helped me a lot. i have adhd, depression/anxiety, autistic traits brain fog and stuff like that and sulforaphane is actually the only My fiancé is on the autism spectrum, and although he’s got a high IQ and can function well enough that most people assume he’s just a bit odd or anti-social rather than autistic, he struggled with a lot of sensory issues, masking fatigue, social anxiety, and some frustration related anger issues (as well as depression and general chronic fatigue and chronic pain related to over-use injuries). Freezing breaks the cell wall allowing the enzyme required for sulforaphane creation to interact with the precursor. EDIT: Actually 100 times more Although an ideal dosage is not known, supplementation of 0. 2. Potential benefits of sulforaphane for Alzheimer's disease [6min 32sec] Sulforaphane and its byproducts may protect against bladder cancer [4min 34sec] What are sulforaphane's effects on cancer? [7min 15sec] Sulforaphane promotes detoxification of heavy metals [5min 13sec] Sulforaphane increases glutathione in the brain [4min 3sec] I used to take Jarrow BroccoMax which contains myrosinase, which is the enzyme your body breaks down and converts to active sulforaphane (which is exactly what happens when you consume it in food), but there's a French company that produced a stabilized version of active sulforaphane. Sulforaphane (SFN) is a dietary phytochemical extracted from cruciferous vegetables. There's approximately 20mg of Sulforaphane per pound of broccoli, the Td50 toxicity rate of Sulforaphane is about 900mg for the average person. It is obtained from cruciferous vegetables such as broccoli, Brussels sprouts, and cabbages. Ideally in company with (hdl) cholesterol, high beta carotene and vitamin B1/thiamine consumption. Personally, I think red cabbage is the best source for sulforaphane. https://pubmed. There is a growing body of research exploring the potential benefits of sulforaphane for individuals with ADHD. so far, i think most of them are not worth the money, what do you guys think?? Yes I don’t believe they work as well (especially when it comes to normalizing the gut microbiome) and broccoli sprouts are easy to grow. Someone replied with a link explaining that sulforaphane is not the good guy rhonda patrick is making it out to be and that there is a negative side to it. As sulforaphane is a natural compound found in cruciferous vegetables, it is a safe and accessible treatment option for individuals with autism. Prostaphane contains 10mg in one capsule, and is produced in France and costs a lot of money. Type "best sulforaphane supplement" in Google and the first link should help you out. Thanks again for the help! I’m trying Sulforaphane as I need detoxification help, but I’m afraid that I could be shooting my self in the foot due to the sulfur component. Serving size is 2 capsules and provides 1,000mg of broccoli sprout powder. Sulforaphane seems to be 'flavor of the month' here after Rhonda Patricks video. im not sure which brand does rhonda patrick recommend, maybe i try and report. It has 1000mg lions mane, 200mg Korean panel ginseng, 320mg bacopa, 250mg rodiola, 10mg vinpocetine and 5mg huperzia extract. Which type of supplement is better? In raw broccoli, the sulforaphane precursor, called glucoraphanin, mixes with the enzyme (myrosinase) when you chew or chop it. BROQ is apparently prostaphane but with new marketing and sold in the US. Studies on sulforaphane and ADHD. In august 2022 SCT was renamed to (CDS) Cognitive Disengagement Syndrome. In a double-blind, placebo-controlled study, 50 adolescent males with ADHD were given either a placebo or sulforaphane-rich broccoli sprout extract for 12 weeks. These will activate NRF2 which will show up activating genes beyond 48 hours. And so people that are sweating, if they're physically active, using the sauna, endurance training, they're losing a lot of magnesium. Listen guys, I've tried almost all stimulants out there except Adderal and prescription ADHD meds (modafinil, selegiline… 77 votes, 117 comments. 331K subscribers in the Supplements community. 1-5. The placebo group received placebo capsules. TLDR: Give sulforaphane a It is a distinct disorder which is frequently misdiagnosed as ADHD-PI, although it is possible to have both, and they are often comorbid. 1 mg for a 250lb person These low quantities are likely attainable via raw broccoli or cruciferious vegetable products Sulforaphane does inhibit CYP2D6 by around 75%. . Crypto Sulforaphane is a compound within the isothiocyanate group of organosulfur compounds. And dosing 40mg of sulforaphane a day from a “trusted” pill would cost me more than the rest of my stack combine. for gut health I'd go for some colostrum like armra. Broccomax is one of the few "sulforaphane" supplements that actually includes the myrosinase needed for the conversion of glucoraphanin into sulforaphane, certainly at that price point, which currently is about $18 for 30-day on Amazon. A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any… May 25, 2021 · Background Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic pathways. ive also heard a good amount of veggies in general is really good for brain development and concentration (i think you mentioned your kiddo having ADHD), but most of all, people with ASD are at a high risk of developing anxiety and depression, and people with ADHD are also high risk for developing depression, and a healthy amount of veggies and This is interesting considering I got prescribed this yesterday and have complete reservations to it. 1 mg for a 250lb person These low quantities are likely attainable via raw broccoli or cruciferious vegetable products You are basically describing one of the main theories of ADHD (see Seeman and Madras 1998 if I recall). Something like 10 times more if I remember correctly. I live in the US and we have very few regulations or enforcements on corp I contributed a post regarding this subject that was deleted from this sub years ago. I did read studies that show that Sulforaphane reduces my particular H2S producing bacteria in the small intestine (which gives me symptoms), which was the biggest motivation to try it. Myrosinase in broccoli is killed when it's cooked, and it's debatable how much if any exists in products like BroccoMax. Adding mustard powder can add more of the enzyme myrosinase that creates the sulforaphane. How many of you use sulforaphane and what brands do you use and how much do you use? I see a variety of price points for supplements, but honestly, I don't know what to trust. But as his mom (adhd/ undiagnosed autistic prob) I need to feel like I am taking what steps I can to support him. Brussel sprouts are crucifers, a family of produce that's pretty well represented in supermarkets. There are also more compounds than sulforaphane in broccoli sprouts. I made the best gains from methyl-B12, methyl-folate, L-Carnitine, magnesium malate, taurine, and niacinamide. They also claim that a single serving will provide 15-20 mg of sulforaphane. I just want to know if that's true cause some people say this dude only tells lies or plants have anti nutrients so I'm wondering is broccoli or that chemical really that good for you ir us it just some kind of vegan myth thanks so much for your input In fact, a metabolite of sulforaphane is sulforaphane-n-acetyl cysteine. It's also known that at lower doses (like the doses humans - even those who eat a lot of broccoli sprouts because their taste buds are apparently non-existent - eat) it is has been shown to be chemoprotective. r/AutisticWithADHD: Community for autistic people with ADHD to ask advice, vent about your day, share stories, infodump on your special interests and… Sulforaphane is a potent dietary activator of the transcription factor Nuclear factor erythroid-like 2 (NRF2), the master regulator of antioxidant cell capacity responsible for inducing cytoprotective genes, but its role in glucose homeostasis remains unclear. Previous clinical trials of oral SF demonstrated positive clinical effects on behavior in young men and changes in urinary metabolomics in children with ASD. Jan 1, 2025 · Most of the sulforaphane capsules that have accurate quantification on the label work out to 400 micrograms (0. 40gr broccoli sprouts + 55C tap water (apparently 70C for 10 minutes increases bioavailability, so I went with the next best/easiest thing), ground up into a shake, let it come to room temp, drink second day today to rule out placebo. Cheap, half the glucoraphanin of mature broccoli, lasts 'forever' in the fridge, commonly eaten raw, easy to slice off ribbons to add to any salad. nih. Put tersely, it's the combination of lethargic and inattentive symptoms. I've tried Jarrow's BroccoMax up to 3 capsules at a time, but it felt very weak compared to normal Broccoli. ncbi. Technically that is correct however it turns into various things such as, glutathione S-transferase, sulforaphane-glutathione, sulforaphane-cysteine, sulforaphane N-acetyl cysteine (SFN-NAC), and sulforaphane-cysteinyl-glycine. All neutral or negative issues with the consumption of sulforaphane are purely speculative and not backed up. No drug interaction questions. It affects both children and adults, and it can have a significant impact on academic, occupational, and social functioning. e. While medication and behavioural th Some suggest using mustard powder on cooked broccoli to recover some of the enzyme needed for sulforaphane production, but the amount of SFN to be made is likely minimal. The precursor and sulforaphane are resistant to heat and therefore cooking, but the enzyme is destroyed. Aug 4, 2024 · 1. 13 hours [159]. Sulforaphane does inhibit CYP2D6 by around 75%. 5-7. On one hand there are supplements with Glucoraphin and Myronaise that form Sulforaphane when ingested. (2018). dopamine and norepinephrine). Listen guys, I've tried almost all stimulants out there except Adderal and prescription ADHD meds (modafinil, selegiline… Rhonda Patrick: "You lose magnesium in sweat, and you lose it in urine. No… Hey guys just seen this dr burger video on sulforaphane and he says it's anti cancerous helps with chronic disease. Apr 29, 2020 · Sulforaphane (1-isothiocyanato-4-methylsulfinylbutane; ACER, Tehran, Iran) was prescribed at 50 μmol and 100 μmol (approximately 10 mg and 20 mg) per day for patients weighing <45 kg and 45–90 kg, respectively. It didn't really do much for me, gave up on that one. She just quickly wrote me a prescription for lamictal without listening. gov/27779894/ Theres significantly more of the precursor to sulforaphane in broccoli sprouts. I hope it helps some of you guys like it did for me. I keep getting misdiagnosed with bipolar with the VA, though I have been diagnosed with PMDD and a hypersomnia disorder and ADHD by outside psychiatrists. 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